Gout, tseem hu ua gouty mob caj dab, yog ib yam kab mob tshwm sim los ntawm hyperuricemia vim muaj kev cuam tshuam hauv purine metabolism lossis uric acid excretion hauv lub cev. Chen Hui, Tus Thawj Coj ntawm Lub Tsev Haujlwm Saib Xyuas Kev Mob ntawm Plaub Lub Tsev Kho Mob ntawm Shanghai Koom Tes rau Tongji University, tau hais rau cov neeg sau xov xwm rau hnub tim 29 tias thaum lub sijhawm mob hnyav ntawm gout tawm tsam, ntxiv rau kev so thiab tshuaj tiv thaiv kab mob, kuj tseem tsim nyog. txhawm rau ntxuav cov kua dej sib xyaw kom sai li sai tau, txo qhov concentration ntawm uric acid crystals thiab inflammatory yam hauv cov pob qij txha, thiab ua txhua yam los tiv thaiv cov pob qij txha.
"Kev rov qab tawm tsam ntawm gout ua kom nrawm sib koom ua ke tsis muaj kev tiv thaiv." Chen Hui tau piav qhia rau cov neeg sau xov xwm rau hnub tim 29 tias gout tsis tsuas yog ua rau mob pob qij txha, tab sis tseem ceeb tshaj, nws tuaj yeem ua rau pob qij txha puas. Kev sib koom ua ke effusion muaj cov ntsiab lus siab ntawm uric acid crystals thiab inflammatory yam, uas ua rau synovial edema, tsim ntawm pob txha mos defects, thiab hnav thiab tsim kua muag ntawm cov pob zeb me me gout. Txawm tias tom qab kev nqus dej, kev tiv thaiv kev tiv thaiv thiab kev tiv thaiv kev tiv thaiv, cov ntaub so ntswg sab hauv ntawm qhov sib koom ua ke tsis tuaj yeem rov qab los rau nws lub xeev ua ntej.
Chen Hui tau hais rau cov neeg sau xov xwm tias nyob rau hauv qhov induction ntawm qee yam, cov qib siab ntawm uric acid nyob rau hauv cov ntshav yuav hloov mus rau cov tshuaj ntsiav thiab cov tshuaj synovial hauv qhov ntau, tsim cov urate crystals. Lub tom kawg nkoos lub cev kom tso cov kua protein uas nplua nuj nyob rau hauv inflammatory yam tseem ceeb rau hauv cov pob qij txha thiab synovial capsule, uas ua rau txo qis hauv cov ntshav uric acid rau ib txwm muaj nuj nqis thiab sib koom tes thiab synovial capsule effusion, o, thiab mob. Gout cuam tshuam rau tag nrho lub cev thiab feem ntau pom nyob rau hauv thawj metatarsophalangeal pob qij txha, pob qij txha, pob qij txha, pob qij txha, thiab ntiv tes, lub luj tshib, thiab pob qij txha. Raws li tus kab mob loj tuaj, nws kuj tuaj yeem cuam tshuam rau thaj chaw xws li cov hlab ntsha synovial, cov leeg nqaij, thiab cov leeg nqaij ib ncig ntawm cov pob qij txha.
Chen Hui tau qhia txog qhov xwm txheej uas tus neeg muaj hnub nyoog 62 xyoos Zhang Abbo (ntse npe) tau mob gout tau ntau xyoo, thiab ntau cov pob qij txha hauv nws lub cev tau o thiab deformed vim muaj pob zeb pob zeb sib sau. Tsis ntev los no, nws tau ntsib ib qho kev phais uas ua rau muaj mob hnyav ntawm gout, uas ua rau nws nyuaj rau pw tsaug zog txhua hmo. Pab pawg Chen Hui tau tsim kho cov kab noj hniav sib koom ua ke rau Zhang Abbo. Nyob rau hauv cov tshuaj loog hauv zos, cov kws kho mob tau ua ib rab koob zoo rau ntawm cov kab mob sib koom ua ke ntawm Zhang Abbo, tom qab ntawd rov ua dej ntxiv nrog rau lub cev saline. Tom qab cov dej sib xyaw ua ke ntawm microneedle, cov tsos mob ntawm qhov liab, o, kub, thiab mob hauv thaj chaw cuam tshuam xws li Zhang lub hauv caug pob qij txha thiab metatarsophalangeal sib koom tau sai sai, thiab thaum kawg nws tau pw tsaug zog. Nws tau ua tiav tawm hauv tsev kho mob.
"Tam sim no, cov tshuaj kho mob rau cov mob gout tawm tsam muaj xws li nonsteroidal analgesics, colchicine, thiab glucocorticoids, nrog rau kev kawm ntawm 2 lub lis piam. Kev sib koom ua ke thiab cov kua dej synovial thiab uric acid crystals Qhov tsis zoo ntawm cov tshuaj no ua ntej, kev phais tom qab 'kev kho mob sib txuas yog tias nws tsis tuaj yeem txo cov kua dej sib koom ua ke thiab mob thaum ntxov ntawm kev tawm tsam, thiab muaj kev phais mob hauv cov theem tom qab. ." Chen Hui tau hais tias nrog kev siv thev naus laus zis cuam tshuam tsawg kawg nkaus, lub tuam tsev kho mob tau tsim kho tshiab - kev sib koom ua ke ntawm cov kab noj hniav thaum ntxov, uas tuaj yeem pab tau zoo rau cov teeb meem saum toj no.
Chen Hui tau qhia tias kev kho kab mob sib koom ua ke tsis tas yuav tsum tau phais, tab sis siv cov koob txhaj tshuaj zoo nyob rau hauv kev taw qhia ultrasound kom raug rau cov kab mob sib koom ua ke. Tom qab ua tiav, sim tshem tawm cov kua dej ntau li ntau tau, tom qab ntawd yaug dua nrog dej tsis huv, thiab thaum kawg txhaj tshuaj tiv thaiv kab mob xws li kev kho mob trioxide.
"Cov kev ua haujlwm no tuaj yeem tsim qhov chaw qis qis rau cov kab noj hniav sib koom ua ke, txo cov kua dej sib xyaw, ua kom cov kab mob luv luv, thiab tiv thaiv cov pob qij txha. Ntawm qhov tod tes, lawv tuaj yeem txo cov tshuaj noj ntawm qhov ncauj, yog li txo cov plab hnyuv, daim siab. , thiab lub raum puas tsuaj los ntawm cov tshuaj. " Chen Hui tau hais tias kev kho mob yog ua raws li kev tshuaj loog hauv zos, thiab cov neeg mob tsis muaj mob thiab rov zoo sai tom qab phais. Nrog kev pab los ntawm ultrasound, cov qauv anatomical sab hauv tuaj yeem raug txheeb xyuas los ntawm daim tawv nqaij, ua tiav "ib rab koob rau hauv qhov chaw" thiab saib xyuas lub sijhawm tiag tiag ntawm cov dej ntws tawm.
